Doctor Laura Denby
Senior Lecturer ORCID 0000-0003-1277-708X
Doctor Laura Denby
Senior Lecturer ORCID 0000-0003-1277-708X
Accepting PhD Students


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Research in a nutshell

My group’s primary area of research is to understand the molecular mechanisms underpinning injury and repair processes in the kidney and in the cardiovascular system. Our key goal is to identify and translate novel therapeutics that can slow/prevent/reverse kidney injury, in particular kidney fibrosis. Our research focusses on using a combination of transcriptomic studies (via RNA-, small RNA-, spatial and single cell RNA-Seq studies), informative rodent models of kidney injury and repair and human patient samples to dissect the complex interplay between the kidney parenchyma, myeloid cells and fibroblasts driving injury or resolution to identify new therapeutic targets and diagnostics for disease severity.


Education/Academic qualification

Gene Therapy, Doctor of Philosophy (PhD), Gene Therapy for Cardiovascular Disease, School of Cardiovascular & Metabolic Health , University of Glasgow , Glasgow , UK
Award Date: 6 Jul 2005

Pharmacology, Bachelor of Science (Honours), Institute of Medical Sciences, University of Aberdeen
Award Date: 5 Jul 2000

External positions

Grants Panel Member, Kidney Research UK
Jul 2022 → …

UK Kidney Association Elected Renal Scientist
Apr 2021 → …


Sonoporation of human renal proximal tubular epithelial cells in vitro to enhance the liberation of intracellular miRNA biomarkers

In: Ultrasound in Medicine and Biology (UMB)

Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis